Experimental studies suggest that coffee and caffeine may potentially help protect against the development of colorectal cancer, but observational studies have not shown a beneficial relationship. The Challenge: Many people around the world drink coffee, and the number keeps rising. Next, we’ll examine stool samples from CPS-3 participants in the Gut Microbiome Sub-study to learn more about the relationship between caffeinated and decaffeinated coffee with the gut microbiome.” ![]() We found that only those who drank decaffeinated coffee had a lower risk of colorectal cancer, regardless of their smoking status. ![]() “To explore further, in this study we looked at coffee drinkers who developed colorectal cancer in the CPS-II Nutrition cohort. Area of Focus: Population Science “In a previous ACS study that used data from the full 1.2 million men and women in the CPS-II cohort, we found that coffee drinkers who didn’t smoke had a lower risk of death from colorectal cancer, and their risk was slightly lower if they drank decaffeinated coffee.
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